Karyotypes can be studied to determine an organism’s chromosomal makeup and to detect genetic defects. Down syndrome is a genetic disorder that is also called trisomy 21. What would trisomy 21 look like in a karyotype? missing chromosome 21 extra chromosome 21 missing sex chromosome extra sex chromosome
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extra number 21
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The karyotype of trisomy of the 21st chromosome has an extra 21st chromosome.
- The total number of chromosomes in a person suffering a trisomy is 45.
- Trisomy is a genetic condition in which an extra copy of a chromosome occurs.
- Thus the karyotypic representation of trisomy is as (44+1 AA, XX/XY).
- In Down's syndrome, the person has a pair of sex chromosomes with 22 pairs of autosomes and an additional copy of the 21st chromosome.
- Persons with Down's syndrome have many abnormalities like short stature and stunted growth, mental retardation, and protruding furrowed tongue.
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