Science, asked by contact2ajay0429, 8 months ago

Keratohyalin granules are a characteristic of​

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Answered by randhirsinghrana13
1

Answer:

Keratohyalin granules are important in the formation of the protective skin barrier and the terminal differentiation of the epidermis. FLG is associated with keratin intermediate filaments in the outer granular layer of the epidermis, and it supports their packing into bundles.

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Answered by khushi27749
2

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HERE U CAN CLEAR YOUR CONCEPTS REGARDING KERTOHYALIN GRANULES ----

Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer. These cells contain keratohyalin granules, which are filled with histidine- and cysteine-rich proteins that appear to bind the keratin filaments together.Epidermolytic hyperkeratosis (EHK) is a condition characterized by abnormal keratohyalin granules, caused by a defect in keratins 1 and 10, resulting in a distinct histologic presentation.

Keratohyalin granules primarily exist within the stratum granulosum, with some present in the stratum spinosum. These granules are insoluble in water and located within the cytoplasm where they promote dehydration of the cell.  Their chief function seems to be cross-linking of keratin filaments which creates the tight barrier that is the epidermis, providing the body with an impermeable layer that protects from invasion by foreign particles.  This process of cornification of the epidermis effected by KHG is known as keratinization.

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