Kreb s cycle
Fats
ct :
With the help of information
collected from internet, prepare the
slides of various stages of mitosis
and observe under the compound
microscope.
Answers
Answer:
Explanation:
It is also known as TriCarboxylic Acid (TCA) cycle. In prokaryotic cells, the citric acid cycle occurs in the cytoplasm; in eukaryotic cells, the citric acid cycle takes place in the matrix of the mitochondria.
The cycle was first elucidated by scientist “Sir Hans Adolf Krebs” (1900 to 1981). He shared the Nobel Prize for physiology and Medicine in 1953 with Fritz Albert Lipmann, the father of ATP cycle.
The process oxidises glucose derivatives, fatty acids and amino acids to carbon dioxide (CO2) through a series of enzyme controlled steps. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels by oxidising them, which are transported by activated carriers NADH and FADH2 to the electron transport chain. The Krebs Cycle is also the source for the precursors of many other molecules, and is therefore an amphibolic pathway (meaning it is both anabolic and catabolic).
The Net Equation
acetyl CoA + 3 NAD + FAD + ADP + HPO4-2 —————> 2 CO2 + CoA + 3 NADH+ + FADH+ + ATP
Reaction 1: Formation of Citrate
The first reaction of the cycle is the condensation of acetyl-CoA with oxaloacetate to form citrate, catalyzed by citrate synthase.
Once oxaloacetate is joined with acetyl-CoA, a water molecule attacks the acetyl leading to the release of coenzyme A from the complex.