krebs cycle process and explanation with diagram
Answers
Krebs cycle is considered as amphibolic pathway
it means, used for both break-down(catabolism) and build-up (anabolism) reactions.
Respiratory pathway is mainly a catabolic process which serves to run the living system by providing energy.
krebs cycle is the major pathway for the synthesis of reduced coenzymes and controlled release of energy during respiration.
The pathway produces a number of intermediates.
Many of them are raw materials for building up the both primary and secondary metabolites
Acetyl Co A is helpful not only in using fatty acids in krebs cycle but also raw material for synthesis of fatty acids, steriods, terpenes, aromatic compounds and carotenoids.
α-keto glutarate is organic acid which forms glutamate on amination.
The citric acid cycle (CAC) – also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle– is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into adenosine triphosphate (ATP) and carbon dioxide. In addition, the cycle provides precursors of certain amino acids, as well as the reducing agent NADH, that are used in numerous other reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.[3][4] Even though it is branded as a 'cycle', it is not necessary for metabolites to follow only one specific route; at least three segments of the citric acid cycle have been recognized.