Question

Limitations of serum ferritin to predict liver iron concentration responses to deferasirox therapy in patients with transfusion-dependent thalassemia

Answer 1

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Limitations of serum ferritin to predict liver iron ... to deferasirox therapy in patients with transfusion-dependent ... thalassaemia before and after 1 yr of deferasirox.

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Answer 2

Ideally, patients will achieve and maintain a serum ferritin value of below 1000 ng/mL, which is associated with higher survival rates and improved cardiac and liver function than higher serum ferritin levels 3, 9. Appropriate chelation therapy has been shown to reduce liver and myocardial iron overload.