Question

Lipid composition of neuronal cell bodies and neurites from cultured dorsal root ganglia

Answer 1

Lipid composition of neuronal cell bodies and neurites from cultured dorsal root ganglia. ... The lipid composition of neuronal somata and neuritic processes of cultured root ganglia has been determined. Neuronal soma contained 37% of dry weight as lipid (15.4% cholesterol, 4.8% galactolipid, and 57.1% phospholipid).

Answer 2

From cultured root ganglia, it is determined that the neuronal soma contains 37% of dry weight as lipid.

Explanation:

• This 37% includes 15.4% of cholesterol, 4.8% of galactolipid, and 57.1% of phospholipid. Phosphatidylcholine and phosphatidyl ethanolamine are the major phospholipids observed.
• The molar ratio of galactolipids which consisted of cerebroside and sulfatide was 2:1. Tetrasialo-, disialo-, and monosialoganglioside were present in the neuronal soma.
• However, 15% of the dry weight as lipid was contained in neurites with 22.1% of cholesterol, 7.7% of galactolipid and 56.4% total phospholipid and the molar ration of cerebroside and sulfatide was 2:1. Higher neuritic galactolipid content was observed.

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