Question

List 5 advantage disadvantage of using animal modern

Answer 1

Small animal models offer the easiest way to keep animals at low costs for longer time with a high reproduction rate. The offer of markers for laboratory use is the biggest in the market. There is also the possibility to work with knock-out animals. On the other hand clinical situation is far away.

Disadvantages are high costs, high personal and work effort, limitation of follow-up period and availability of markers to study special histological issues.

Middle sized animal models in rabbits offer the possibility to provoke paraplegia by clamping the infrarenal aorta only. This reduces operating time and work effort. It is possible to investigate animals for several days. The disadvantages is a little marker offer to examine special questions in the laboratory.

Small animal models offer the easiest way to keep animals at low costs for longer time with a high reproduction rate. The offer of markers for laboratory use is the biggest in the market. There is also the possibility to work with knock-out animals. On the other hand clinical situation is far away. Results must be interpret very carefully and often require further studies in larger animal models.

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