list the disadvantages of using computer models instead of using clinical trials for testing medicines
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Answer:
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Explanation:
Computer simulations are a faster, cheaper and effective alternative to animal experiments—and they will soon play an important role in the early stages of drug development. Animal testing is used in pharmaceutical and industrial research to predict human toxicity, and yet analysis suggests that animal models are poor predictors of drug safety in humans. The cost of animal research is high—in dollars, delays in drug approval, and in the loss of potentially beneficial drugs for human use. Human subjects have been harmed in the clinical testing of drugs that were deemed safe by animal studies. Increasingly, investigators are questioning the scientific merit of animal research. This review discusses issues in using animals to predict human toxicity in pharmaceutical development. Part 1 focuses on scientific concerns over the validity of animal research. Part 2 will discuss alternatives to animal research and their validation and use in production of human pharmaceuticals.
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Explanation:
Researchers have developed a wide range of sophisticated computer models that simulate human biology and the progression of developing diseases. Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.” Says PETA.
“Scientists at private companies, universities and government agencies are developing new cell and tissue tests, computer models and other sophisticated methods to replace existing animal tests. These alternatives are not only humane; they also tend to be more cost-effective, rapid and reliable than traditional animal tests.” Says the Humane Society of the United States.
“But research shows computer simulations of the heart have the potential to improve drug development for patients and reduce the need for animal testing.” Says Scientific American.
“Computer models could replace animal testing.” Reads the headline of Global Biotech Insights.