main difference between coagulant fixative and non coagulant fixative..?? help please
Answers
Explanation:
Considering the mechanism of fixation, fixatives can be classified in two types: coagulant and cross-linking. ... Cross-linking fixatives form chemical bonds between molecules of the tissue. Alcoholic fixatives are coagulants, such as Bouin and Carnoy, whereas formaldehyde and glutaraldehyde are cross-linking fixatives
Answer: It is explained as follows:
Explanation:
Fixation is the process by which cells or tissue are fixed in physical state and partially in chemical state so they can withstand further treatment with minimum of loss or distortion.
Fixatives function by precipitating or denaturing proteins, which then cross-link to form a meshwork.
On the basis of how they affect soluble proteins in solution, fixatives are coagulant or non-coagulant. The main difference between them is that non-coagulant fixatives, which are additive in nature, generate extensive cross-links and produce a less permeable gel while coagulant fixatives are believed to produce a permeable meshwork of protein strands.
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