Question

Maintenance of genomic (DNA) integrity is essential in passing traits from parent to offspring. Although radiation is all around us, some types of radiation in small doses may not be harmful. However, large doses of ionizing radiation , e.g. nuclear tests, can damage DNA within cells. French researchers, Bergonie and Triondeau, determined that rapidly dividing and immature less differentiated cells are most susceptible to damage by ionizing radiation.


Which type of cell and in which cell cycle phase is the DNA of that cell type MOST susceptible to damage by ionizing radiation?
A
spermatogonia in the M phase

B
neurons (nerve cells) in the G1 phase

C
multinucleated skeletal muscle cells in the Go phase

D
bone (specifically osteoclasts) at the end of the S phase before they differentiate

Answer 1

Answer:

hope it helps you

Explanation:

HeLa cells in M phase were the most sensitive to X-ray cell killing, G1 and G2 were the most radioresistant, and S-phase cells were intermediately sensitive. These results have been reproduced in other mammalian cell lines generally yielding the same variation in cell cycle radiosensitivity (8).