Question

Major steps involved in process of gluconeogenesis

Answer 1

There are three steps in glycolysis that are energetically irreversible:

hexokinase, phosphofructokinase (PFK), and pyruvate kinase.

The gluconeogenic pathway is thus a mixture of six enzymes that are needed to bypass these three irreversible steps, plus the remainder of the glycolytic steps, which are reversible.

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