Mechanism of action of azathioprine as immunoglobulin
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❄Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins.
❄It may also interfere with cellular metabolism and inhibit mitosis.
❄Its mechanism of action is likely due to incorporation of thiopurine analogues into the DNA structure, causing chain termination and cytotoxicity.
Hope it is helpful ✌
Here's the answer ⤵
❄Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins.
❄It may also interfere with cellular metabolism and inhibit mitosis.
❄Its mechanism of action is likely due to incorporation of thiopurine analogues into the DNA structure, causing chain termination and cytotoxicity.
Hope it is helpful ✌
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Azathioprine
Targets (2)Enzymes (6)Biointeractions (7)
IDENTIFICATION
Name-Azathioprine
Type-Small Molecule
Groups-Approved
Description
An immunosuppressive antimetabolite pro-drug. It is an imidazolyl derivative of 6-mercaptopurine and many of its biological effects are similar to those of the parent compound. Azathioprine is converted into 6-mercaptopurine in the body where it blocks purine metabolism and DNA synthesis
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