Question

Mechanism of action of flavanoids on immune cells

Answer 1

Effect of plant flavonoids on immune and inflammatory cell function
Elliott Middleton
Flavonoids in the living system, 175-182, 1998
The flavonoids are a large group of naturally occurring phenylchromones found in fruits, vegetables, grains, bark, roots, stems, flowers, tea, and wine. Up to several hundred milligrams are consumed daily in the average Western diet. Only limited information is available on the absorption, distribution, metabolism, and excretion of these compounds in man. Some compounds are absorbed, however, and measurable plasma concentrations are achieved which could have pharmacological relevance.
A variety of in vitro and in vivo experiments have shown that selected flavonoids possess antiallergic, antiinflammatory, antiviral and antioxidant activities. Moreover, acting by several different mechanisms, particular flavonoids can exert significant anticancer activity including anticarcinogenic properties and even a prodifferentiative activity, amongst other modes of action.

Hope u like the ans.. Plse Mark me as brainlist

Answer 2

Chemically, flavonoids have a polyphenolic structure that attracts antioxidant activities on them.In an inflammation context some of the flavonoids' action mechanisms such as acting as antioxidants, modulating gene expression for example cytokines, adhesion molecules or enzyme activities.The flavonoids  can be acquired from natural plans and fruits .The examples are vegetables and roots ,tree barks ans even the fruits .