mechanism of blood clotting?
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The mechanism of blood clotting involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin.
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A platelet plug is formed, and the external bleeding stops. Next, small molecules, called clotting factors, cause strands of blood-borne materials, called fibrin, to stick together and seal the inside of the wound. Eventually, the cut blood vessel heals and the blood clot dissolves after a few days.
three steps that occur in a rapid sequence:
(1) vascular spasm, or vasoconstriction, a brief and intense contraction of blood vessels;
(2) formation of a platelet plug; and
(3) blood clotting or coagulation, which reinforces the platelet plug with fibrin mesh that acts as a glue to hold the clot.
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