Science, asked by tejeshreena4069, 1 year ago

Mechanism of hoffmann bromamide degradation reaction

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Answered by shariquekhan2500
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The answer is given below
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kappa: it's still not full :/
Answered by ItzSanam126
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ANSWER:

✔Hoffmann developed a method for preparation of primary amines by treating an amide with bromine in an aqueous or ethanolic solution of sodium hydroxide.

✔In this degradation reaction, migration of an alkyl or aryl group takes place from carbonyl carbon of the amide to the nitrogen atom.

✔The amide so formed contains one carbon less than that present in the amide.

⭐Reaction ----

RCONH2 + Br2 +4NaOH ➡RNH2 + Na2CO3 + 2NaBr + 2H2O

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