mechanism of hormone action ???
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Explanation:
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Answer:
Mechanism of Hormone action
Hormones effects target cells by binding to hormone receptors (specific proteins). Each hormkme bindsto it's specific proteins. Hormones receptors present in the target cells are of 2 types :
- Membrane bound receptors present on cell membrane of target cells.
- Intracellular receptors present inside the target cells, mostly nuclear receptors.
Binding with the receptors, it forms : Hormone receptor complex. The Hormone receptor complex further leads to certain changes in the target cells. And hence the hormones regulate the functions.
The hormones are of 4 types based on chemical nature :
- Peptide, Polypeptide, Protein Hormones : Insulin, Glucagon, Pituitary Hormone, Hypothalamic Hormone
- Steroids : Cortisol, Testosterone, Estradiol, Progesterone
- Iodthyronines : Thyroid Hormone
- Amino acid derivatives : Epinephrine
Hormones that bind with membrane bound receptors do not enter the cell, but helps in generating second messengera like cyclic AMP, Ca++ and IP3 which regulates cellular metabolism.
Hormones (Steroid hormones and Iodthyronines, etc.) which bind with intracellular receptors, regulate the gene expression and chromosome function by interacting with the genome.