Mechanism of muscle contraction including physical molecular and biochemical basis of muscle contraction
Answers
The molecular basis of muscle contraction. Muscles contract by the interdigitation of protein filaments within them. These filaments are made up of myosin and actin molecules. ... These probes can detect conformational changes during single cycles of the myosin ATPase using fluorescence stopped-flow kinetic methods.
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Calcium is released from the sarcoplasmic reticulum at the time of muscle contraction ....
This calcium binds with Stark troponin I tropomyosin Complex on the actin filament molecules ....
the complex shifts and the myosin binding sites on actin filaments are exposed ...
Myosin head have actin binding sites as well as ATP sites..
Myosin head binds with the actin filaments and hydrolysis of ATP takes place that pushes the thin actin over the thick myosin filament ...
The thin filaments slide over the thick filament according to sliding filament theory...
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