MEM derivative is used for the protection of
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β-Methoxyethoxymethyl ether (MEM) – Removed by acid. Dimethoxytrityl, [bis-(4-methoxyphenyl)phenylmethyl] (DMT) – Removed by weak acid. DMT group is widely used for protection of 5'-hydroxy group in nucleosides, particularly in oligonucleotide synthesis.
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Answer:
Explanation:
β-Methoxyethoxymethyl ether (MEM) – Removed by acid. Dimethoxytrityl, [bis-(4-methoxyphenyl)phenylmethyl] (DMT) – Removed by weak acid. DMT group is widely used for protection of 5'-hydroxy group in nucleosides, particularly in oligonucleotide synthesis.
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