Mention any two ways in which Single Nucleotide Polymorphisms (SNPs) identified in human genome, can bring out revolutionary changes in biological and medical sciences.
Answers
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A single-nucleotide polymorphism, often abbreviated to SNP, is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).
For example, at a specific base position in the human genome, the C nucleotide may appear in most individuals, but in a minority of individuals, the position is occupied by an A. This means that there is a SNP at this specific position, and the two possible nucleotide variations – C or A – are said to be alleles for this position.
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Single Nucleotide Polymorphisms (SNPs) identified in human genome:
Single nucleotide polymorphisms, shortly called SNPs (articulated "cuts"), and are the most widely recognized sort of hereditary variety among individuals. Every SNP speaks to a distinction in a solitary DNA building square, called a nucleotide.
For instance, a SNP may supplant the “nucleotide cytosine (C) with the nucleotide thymine” (T) in a specific stretch of DNA.
SNPs happen ordinarily all through an individual's DNA. They happen once in each 1,000 nucleotides by and large, which means there are around 4 to 5 million SNP’s in an individual's genome.
These varieties might be exceptional or happen in numerous people. Researchers have discovered in excess of 100 million SNP's in populaces around the globe.
Two ways:
- In Human Genome at particular base positions, most individuals would be familiar with C nucleotides.
- In minority individuals the position occupied is done by A. Two possible nucleotide variations C or A.
Uses:
- It can be used to trace the hereditary information and history of the human evolution.
- It is also used in location place of the chromosome of the interest.