Mention the chemical change that proinsulin undergoes, to be able to act as mature insulin.
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The proinsulin is cleaved to remove extra stretch called the C-peptide to form mature insulin having only A-chain and B-chain joined by disulphide bond.
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proinuslin
prohormone knowns as proinuslin
mature insulin consists of two short peptidechains
chain A and chain B that are linked together by disulfide bridges.
insulin contains an extra strech called c- peptide
this c-peptide is not present in the mature insulin and is removed during maturation into insulin.
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