Question

Merits and demerits of viral cultivation

Answer 1

Disadvantages of Animal Inoculation

(1)Expensive and difficulties in maintenance of animals.

(2)Difficulty in choosing of animals for particular virus

(3)Some human viruses cannot be grown in animals,or can be grown but do not cause disease.

(4)Mice do not provide models for vaccine development.

(5)It will lead to generation of escape mutants

Issues related to animal welfare systems

Advantages of Animal Inoculation

(1)Diagnosis, Pathogenesis and clinical symptoms are determined.

(2)Production of antibodies can be identified.

(3)Primary isolation of certain viruses.

(4)Mice provide a reliable model for studying viral replication.

(5)Used for the study of immune responses, epidemiology and oncogenesis

Answer 2

Explanation:

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