Metabolic Allergies
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Metabolic food disorders are one example of a food intolerance and are NOT the result of a disorder of the immune system. Metabolic food disorders result from a genetically-inherited defect in the ability to metabolize a food component or a genetically-inherited sensitivity to a food component that affects some critical metabolic process. Lactose intolerance and favism can serve as examples. Lactose intolerance occurs because of an inherited deficiency of the enzyme, β-galactosidase, in the intestinal mucosa. Favism results from an inherited deficiency in the enzyme, glucose-6-phosphate dehydrogenase, in the erythrocytes, which causes a heightened sensitivity to several naturally occurring oxidant compounds found in fava beans.
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