Metabolism and regulation of functional genomics
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Aft1p regulates genes involved in iron metabolism, and Mac1p regulates genes involved in copper homeostasis. Like Zap1p, these factors activate the expression of target genes in metal-limiting conditions, to facilitate uptake and distribution of the metal ion.
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Functional genomics. ... Functional genomics focuses on the dynamic aspects such as gene transcription, translation, regulation of gene expression and protein–protein interactions, as opposed to the static aspects of the genomic information such as DNA sequence or structur
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