MHC functioning way?///////////
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MHC is the tissue-antigen that allows the immune system (more specifically T cells) to bind to, recognize, and tolerate itself (autorecognition). MHC is also the chaperone for intracellular peptides that are complexed with MHCs and presented to T cell receptors (TCRs) as potential foreign antigens.
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The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response. Credit: Juan Gaertner/Shutterstock.com. Their main role is in antigen presentation where MHC molecules display peptide fragments for recognition by appropriate T-cells.
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