Micro-satellites and minisatellites
normally
.Code for several proteins
.Do not code for any proteins
.Form a very small proportion
of human genome
.Show low degree of
polymorphism
Answers
Answer:
Minisatellites are usually defined as the tandem repeats of a short (10- to 100-bp) motif ... New alleles that display changes in the number of tandem copies have been observed at ... Most likely, these events result from the gene conversion repair of ... Furthermore, sequence analysis of a few hypermutable loci has not yet
Explanation:
Answer:
Microsatellites and minisatellites normally do not code for any proteins.
Explanation:
What are repetitive DNA and satellite DNA?
The majority of the human genome is the same among all human beings. The difference between bases in a genome of two different persons is only 0.1%, the rest 99.9% remains the same. Such similar sequences of DNA are known as repetitive DNA.
Now, the whole bulk DNA (genome) is separated from certain DNA sequences during density gradient centrifugation.
The bulk DNA in this process gets separated as a major peak and the other small peaks are referred to as satellite DNA.
What are microsatellites and minisatellites?
The satellite DNA is again divided into two categories based on:
- base composition
- length of each segment, and,
- number of repetitive units
These are microsatellites and minisatellites.
A] MICROSATELLITES:
- The microsatellites are also referred to as VNTRs (Variable number of tandem repeats
- A short sequence of DNA is copied numerous times and arranged tandemly
- The number of copies is a variable parameter from chromosome to chromosome among different individuals
- The size of VNTRs range from 0.1-20 kb
B] MINISATELLITES:
- Also known as SSRs (Single Sequence Repeats) or STRs (Short Tandem Repeats)
- The size ranges from 1-6 bp
General properties of satellite DNA:
The satellite DNA:
- Do not code for any proteins
- Show a very high degree of polymorphism
- They are very effective and form the basis of the DNA fingerprinting technique.
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