Question

Mild lymphoplasmacytic infiltration with occasional eosinophils along with oedema

Answer 1

Eosinophilic fasciitis (EF), first described by Shulman in 1974, is a rare disorder of unknown etiology characterized by symmetric and painful swelling with progressive induration and thickening of the skin and soft tissues.1-3 In Korea, EF was first reported in 1980.4 Inflammation of the fascia is not associated with exposure to toxic chemicals or with collagen vascular disease. Peripheral eosinophilia is frequently present,5,6 and a good response to systemic corticosteroid therapy is characteristic of EF. In this case, we describe a 19-year-old female with EF whose only initial symptom was symmetric pitting edema in her lower legs without skin abnormalities.


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Answer 2

that infiltrate the epithelium in more than occasional numbers, coalesce to form aggregates, or show extensive.