Question

Mixture of ammonium chloride and ammonium hydroxide is buffer solution

Answer 1

Answer:

Ammonium chloride is the salt component of ammonium chloride-ammonium hydroxide buffer system that completely inhibits the BVDV infection of MDBK cells when present at a concentration of 50 mM . Viruses treated with ammonium chloride (NH4Cl) results in loss of infectivity because it neutralizes the pH of endosome.

Answer 2

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NH4OH, being a weak base, ionizes to a less extent while NH4Cl being a strong electrolyte ionizes almost completely. When a small amount of strong acid like HCl is added, the H+ ions combines with OH- to form un-dissociated water molecules. However, to maintain Ka constant, NH4OH dissociates more thus removing H+ ions.

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