Question

Modulatory effects of curcumin, silybin-phytosome and alpha-r-lipoic acid against thioacetamide-induced liver cirrhosis in rats

Answer 1

Answer:

Liver cirrhosis is the final consequence of a progressive fibrotic process characterized by  

excessive collagen deposition and destruction of the normal liver architecture. This study  

aimed to investigate the protective effects of curcumin, silybin-phytosome and alpha-R-lipoic  

acid against thioacetamide-induced cirrhosis. Male rats were allocated into five groups of  

which one group received saline and served as normal control. Animals from groups 2–5  

were treated with thioacetamide administered intraperitoneally at a dose of 200 mg/kg 3 …

Explanation: