Question

monoclonal antibodies and its clinical applications

Answer 1

Although monoclonal antibody technology has only been with us for slightly more than 10 years, it has already had a great impact on both basic science and clinical medicine. The ability to use these antibodies as highly specific and sensitive reagents that are consistent from batch to batch is invaluable. Because of this ability, monoclonal antibodies are assuming an ever more important role in laboratory assays. In addition, immunohistochemical techniques employing monoclonal antibodies enhance the histologic characterization of pathologic specimens. These clinical benefits are real but are often hidden from the eyes of the physician taking care of his patient. However, other newer uses of monoclonal antibodies are much more spectacular. Clinical imaging with monoclonal antibodies has been shown to be feasible in a variety of systems. Antibodies to colon cancer and melanoma have detected metastatic tumors that were otherwise hidden clinically. ..

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