mutarotation and haworth perspective formula of carbohydrates ( importance and advantage )
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The rate of mutarotation (the process by which reducing sugars may undergo structural changes in solution, for example between α- and β-anomers via an open-chain aldehyde containing form) increases with temperature and is affected by pH, bases being particularly effective. For pyranose-pyranose interconversions, the minimum rate is observed in acidic conditions (pH 2.5-6) but the exact value for HS oligosaccharides has not, to our knowledge, been determined. The polarity of the solvent is also a factor, with polar solvents promoting mutarotation (3–5).
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