Question

Mutations that influence bipolar disorder and schizophrenia

Answer 1

15

SCI-TECH

SCI-TECH

Mutations that influence bipolar disorder, schizophrenia identified

People from the same family studied shared some genetic variations while also having unique ones.

People from the same family studied shared some genetic variations while also having unique ones. | Photo Credit: BenGoode

R. Prasad

15 DECEMBER 2018 17:43 IST

UPDATED: 15 DECEMBER 2018 17:45 IST

Researchers have identified 42 rare mutations in the genes implicated in very severe mental disorders

By sequencing the exome (the part of the genome composed of exons that gets translated into proteins) of 32 people from eight families who suffer from mental illness such as bipolar disorder, schizophrenia and psychosis, Bengaluru-based researchers have identified 42 rare mutations in the genes implicated in very severe mental disorders.

Answer 2

Answer:

As reported in the journal Molecular Psychiatry, the researchers identified mutations in a gene called ANT1 among patients with bipolar disorder. They then examined mice that lacked ANT1 in the brain