Biology, asked by harshasss832, 1 year ago

Name some situations in which the endogenous ligand of a new biological target may not serve as a good lead compound

Answers

Answered by Anonymous
0
Advantages
• You do not have to be creative. 
• You do not have to understand what causes the disease state.
• You can test whatever becomes available. 
• You may get hits with compounds that would not have been tested in a rational approach because structures are unrelated to what you think should be important
Disadvantages 
• There are an almost infinite number of possibilities.
• You may be testing compounds completely unrelated to the biological system that is important. 
• Time and expense may be excessive.
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