name the activator of gastric proteases
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The gastric aspartic proteinases are synthesized in the gastric mucosa as inactive precursors.
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Precursor. Pepsin is expressed as a zymogen called pepsinogen, whose primary structure has an additional 44 amino acids compared to the active enzyme. In the stomach, gastric chief cells release pepsinogen. This zymogen is activated by hydrochloric acid (HCl), which is released from parietal cells in the stomach lining.
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