Question

Name the toxic substance that is responsible for chill and fever in Malaria.​

Answer 1

Answer:

Pathogenesis. The fever and chills of malaria are associated with the rupture of erythrocytic-stage schizonts. In severe falciparum malaria, parasitized red cells may obstruct capillaries and postcapillary venules, leading to local hypoxia and the release of toxic cellular products.

Answer 2

Answer:

haemozoin is the toxin.

Explanation:

the sporozoites rupture the red blood cells and this results in the release of a toxic substance called haemozoinwhich is responsible for chill and high fever, recurring every three to four days.