neurochemical abnormality most closely to schizophernia
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In essence, the dopamine hypothesis states that the neurochemical abnormality associated with schizophrenia involves an excessive amount of dopamine due to over active neurotransmission or the presence of extra D2 receptors.
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ɪɴ ᴇssᴇɴᴄᴇ, ᴛʜᴇ ᴅᴏᴘᴀᴍɪɴᴇ ʜʏᴘᴏᴛʜᴇsɪs sᴛᴀᴛᴇs ᴛʜᴀᴛ ᴛʜᴇ ɴᴇᴜʀᴏᴄʜᴇᴍɪᴄᴀʟ ᴀʙɴᴏʀᴍᴀʟɪᴛʏ ᴀssᴏᴄɪᴀᴛᴇᴅ ᴡɪᴛʜ sᴄʜɪᴢᴏᴘʜʀᴇɴɪᴀ ɪɴᴠᴏʟᴠᴇs ᴀɴ ᴇxᴄᴇssɪᴠᴇ ᴀᴍᴏᴜɴᴛ ᴏғ ᴅᴏᴘᴀᴍɪɴᴇ ᴅᴜᴇ ᴛᴏ ᴏᴠᴇʀ ᴀᴄᴛɪᴠᴇ ɴᴇᴜʀᴏᴛʀᴀɴsᴍɪssɪᴏɴ ᴏʀ ᴛʜᴇ ᴘʀᴇsᴇɴᴄᴇ ᴏғ ᴇxᴛʀᴀ ᴅ2 ʀᴇᴄᴇᴘᴛᴏʀs.
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