Non-competitive inhibitor of an enzyme catalyzed reaction
A.decreases Vmax
B. binds to Michaelis complex (ES)
C. both (a) and (b)
D. can actually increase reaction velocity in rare cases
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YOUR ANSWER IS OPTION (C)
BOTH A AND B
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YOUR ANSWER IS OPTION (C)
BOTH A AND B
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Non-competitive inhibitor of an enzyme
Explanation:
- A type of enzyme inhibition in which the inhibitor does not binds to the active site instead it get attached to the allosteric site and reduces the activity of the enzyme is called non-competitive inhibition.
- These inhibitors can bind with enzyme as well as enzyme substrate complex.
- It inhibits by binding irreversibly to the enzyme but not at the active site.
- Vmax decreases with pure non-competitive inhibition.
- As the inhibitor binds to the allosteric site so it can bind to Michaelis complex (ES) also.
- Hence, it is concluded that option C. both (a) and (b) is the correct answer.
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