Non-protein nitrogenous substances found in the plasma
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urea, biuret and ammonia. these can be found in serum , plasma, urine , amniotic fluid and other body fluids.
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Non-protein nitrogenous substances (NPN): The most important NPN compounds used in evaluation of kidney functions are urea, creatinine, creatine uric acid, and ammonia. As clearance levels decrease, blood levels of creatinine, urea, and uric acid increase.
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