Question

Non-systemic antacid which produces systemic effect upon reaction with gastric HCl is​

Answer 1

Answer:

Non Systemic antacids

In Magnesium salt, Magnesium carbonate is most water soluble and reacts with HCl at a slow rate, while Magnesium hydroxide has low solubility and has the power to absorb and inactivate pepsin and to protect the ulcer base.

Answer 2

Answer:

Magnesium carbonate is the Non-systemic antacid that produces a systemic effect upon reaction with gastric HCl.

Explanation:

Non-systemic antacids are insoluble and are poorly absorbed. They not only neutralize HCl but also bind to bile acids, reduce the activity of pepsin, and stimulate the production of prostaglandins.

• When magnesium carbonate is taken as a non-systemic antacid for issues like gastrointestinal symptoms, heartburn, constipation, gastroesophageal reflux, etc, it mixes with the water more readily and slowly reacts with gastric HCl, as it reacts with HCl in the stomach to form carbon dioxide and magnesium chloride, thereby neutralizing the excess acid present in the stomach.

• It is frequently used to manage a condition called Uremia.