Normal hearing in humans is determined by the presence of two dominant genes D and E. If the person has only one dominant gene (D ee, ddE-) or all recessive (ddee) he is deaf. Deaf parents have seven children with normal hearing. Determine the genotypes of the parents. Determine the form of gene interaction.
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In addition, at least 58 auditory genes have been identified: 16 for autosomal dominant and 11 for autosomal recessive loci, and 1 for an X-linked locus; 6 mito-chondrial genes and at least 38 genes for syndromic hearing loss have also been discovered (n.b. some genes cause multiple forms of deafness) (Table 1).
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