Novel inhibitors of lasr dependent quorum sensing in pseudomonas aeruginosa
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A microarray analysis has been shown that both compounds were general inhibitors of quorum sensing that is the expression levels of most LasR-dependent genes were affected.
We have focused on a P. aeruginosa quorum-sensing signal that has been shown to be involved in the regulation of a battery of virulence genes.
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- A quorum is a minimum level of interest or attendance required before an official meeting or action can take place. Companies often stipulate the quorum required among shareholders to make decisions, spelled out in the corporate charter.
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