Nuclear membrane disappears during mitosis at–
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The nuclear membrane and nucleolus both disappear during prophase of mitosis and meiosis. ... The nuclear membrane and nucleolus both disappear during prophase of mitosis and meiosis. The nucleolus is a region of the interphase nucleus containing many of the genes that code for ribosomal RNAs (rRNAs).
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Nuclear membrane starts disappearing at the start of mitosis and by the late prophase it disappears completely along with the major cell organelles. The nuclear membrane disappears presumably to allow more space for karyokinesis and proper separation of chromatids.
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