Question

Obese people often have increased blood levels of insulin and insulin-like growth factor-1 (igf-1). (this condition, known as hyperinsulinemia or insulin resistance, precedes the development of type 2 diabetes.) high levels of insulin and igf-1 may promote the development of colon, kidney, prostate, and endometrial cancers (29).

Answer 1

 growth factor (IGF) axis may play a role in glucose ... insulin sensitivity in individuals with and without type 2 ... low IGFBP-1 levels in patients with preexisting insulin.