omalizumab is example of
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Omalizumab is a humanized IgG1 monoclonal antibody that binds IgE. Designed to bind free IgE, omalizumab causes a marked downregulation of the high-affinity IgE-receptor on the surface of mast cells and basophils. It has shown efficacy in severe bronchial asthma and chronic idiopathic urticaria.
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