One strand of ds dna is mutated, changing allthymine to uracil. after one round of replicationof the mutated dna strand, the meltingtemperature of the resulting dna wil
Answers
Explanation:
now turn from DNA replication to DNA mutations and repair. Several types of mutations are known: (1) the substitution of one base pair for another, (2) the deletion of one or more base pairs, and (3) the insertion of one or more base pairs. The spontaneous mutation rate of T4 phage is about 10-7 per base per replication. E. coli and Drosophila melanogaster have much lower mutation rates, of the order of 10-10.
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The substitution of one base pair for another is the a common type of mutation. Two types of substitutions are possible. A transition is the replacement of one purine by the other or that of one pyrimidine by the other. In contrast, a transversion is the replacement of a purine by a pyrimidine or that of a pyrimidine by a purine.
Watson and Crick suggested a mechanism for the spontaneous occurrence of transitions in a classic paper on the DNA double helix. They noted that some of the hydrogen atoms on each of the four bases can change their location to produce a tautomer. An amino group (-NH2) can tautomerize to an imino form (═NH). Likewise, a keto group