origin of action potential
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Action potentials are caused when different ions cross the neuron membrane. A stimulus first causes sodium channels to open. Because there are many more sodium ions on the outside, and the inside of the neuron is negative relative to the outside, sodium ions rush into the neuron.
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Action potentials can originate not only at the axon hillock, but also in the axon initial segment, 30–40 μm from the soma and close to the first myelinated segment. In some neurons the action potential even originates at the first node of Ranvier, where sodium channels are highly concentrated
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