Question

Outcome measures in assessing efficacy and safety of warfarin and acitrom in atrial fibrillation

Answer 1

Stop warfarin.Test INR daily until it has returned to the therapeutic range.Restart warfarin with a reduced dose when INR < 5.Give vitamin K 1.0 – 2.5 mg, orally if INR fails to reduce, or if there is high risk of serious bleeding (N.B. subcutaneous administration is not effective)