Overexpression of the erk/map kinases in oral squamous cell carcinoma
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Overexpression of the ERK/MAP kinases in oral squamous cell carcinoma. Extracellular signal-regulated kinases (ERK1 and ERK2), an MAPK subfamily, are activated by many oncogenes, such as ras and raf, and they induce cell proliferation. myc is also an oncogene and one of the targets of ERKs.
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Explanation:
Overexpression of the ERK/MAP kinases in oral squamous cell carcinoma. Extracellular signal-regulated kinases (ERK1 and ERK2), an MAPK subfamily, are activated by many oncogenes, such as ras and raf, and they induce cell proliferation. myc is also an oncogene and one of the targets of ERKs.
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