Pco2 of blood present in the aorta is equal to po2 of blood present in
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The composition of environmental air is approximately 78% nitrogen, 21% oxygen, 1% argon, and trace percentages of carbon dioxide, neon, methane, helium, krypton, hydrogen, xenon, ozone, nitrogen dioxide, iodine, carbon monoxide, and ammonia. Therefore, at sea level where atmospheric pressure is known to be 760 mm Hg, the partial pressures of the various gases can be estimated to have partial pressures of approximately 593 mm Hg for nitrogen, 160 mm Hg for oxygen, and 7.6 mm Hg for argon. However, these partial pressures are not accurate reflections of the partial pressures available for diffusion within the alveoli of the lung. When air is inhaled through the upper airways, it is warmed and humidified by the pulmonary tract. The result of this process introduces the presence of significant levels of water vapor that then adjusts the partial pressures the other gases, including oxygen. It is not possible to collect gases directly from the alveoli. The alveolar gas equation is of great help in calculating and closely estimating the partial pressure of oxygen inside the alveoli. The alveolar gas equation is used to calculate alveolar oxygen partial pressure:
PAO2 = (Patm - PH2O) FiO2 - PaCO2 / RQ
Where PAO2 is the partial pressure of oxygen in the alveoli, Patm is the atmospheric pressure at sea level equaling 760 mm Hg. PH2O is the partial pressure of water equal to approximately 45 mm Hg. FiO2 is the fraction of inspired oxygen. PaCO2 is the carbon dioxide partial pressure in alveoli, which in normal physiological conditions is approximately 40 to 45 mm Hg, and the RQ (respiratory quotient). FiO2 is directly related to the percent composition of oxygen in the inspired air. Without support at sea level, this is 21% or 0.21. However, each liter of supplemental oxygen in the inspired air increases this value by approximately 4% or 0.04. Therefore 2 liters of supplemented oxygen increases the FiO2 at sea level by 8% or 0.08 to 29% or 0.29. The value of RQ can vary depending upon the type of diet and metabolic state of the person. A standard value of 0.82 for the typical human diet. At sea level without supplemented inspired oxygenation, the alveolar oxygen partial pressure (PAO2) is:
notes given by
RISHI.P
Explanation:
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