Peptide array called GCN4 can be fused with dcas 9 protein that can attract effector molecule with single chain fragments. Now the multiple GCN4 SCFV interactions will ensure the engagement of multiple effector molecules to dcas programmed DNA site.
Which of the following method holds good for the above statement ? Select the correct option and give the reason why the respective option is correct.
A. Genome labeling
B. DNA epigenetic editing
C. DNA epigenome editing
D. Fluorescent imaging
E. SunTag
F. SunTaq
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Explanation:
Epigenetics classically refers to the inheritable changes of hereditary information without perturbing DNA sequences. DNA methylation, demethylation, hydroxyl-methylation, histone modification, chromatin remodeling, gene imprinting, and noncoding RNA are the central mechanisms involved. They play important roles in diverse biological processes including gene regulation, iPSC reprogramming and maintenance, genomic imprinting, X-chromosome inactivation, aging, neurodegeneration, autoimmune modulation, and tumorigenesis
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