Biology, asked by nithish5555, 1 year ago

peptidyl transferase plays an important role during protein synthesis. what is true about this enzyme

Answers

Answered by IshitaChakraborty
0
Peptidyl Transferase : It is an aminoacyltransferase as well as the primary enzymatic function of ribosome which forms peptide bonds between adjacent amino acids using tRNAs during the translation process of protein synthesis.

• Formation & Dependence => Peptidyl Transferase is carried out by the ribosome. Its activity is not mediated by any ribosomal proteins but by rRNA, a ribozyme. Ribozymes are the only enzymes which are not made up of proteins but ribonucleotides. All other enzymes are made up of proteins.

• Substrate => The substrate for the enzyme reaction are two RNA molecules, one bearing the growing peptide chain & the other bearing the amino acid that will be added to the chain. The peptidyl chain & the amino acids are attached to their respective tRNAs via ester bonds to the O-atom at the CCA-3' ends of these tRNAs.

• Function => Peptidyl Transferase responsible for catalysing the peptide bond formation reaction between amino acids in the P-site & A-site of a ribosome during translation.
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